EPITOPE SUMMARY
FMNKFIYEI is a linear peptidic epitope (epitope ID
911012
) studied as part of Alpha-fetoprotein (UniProt:P02771) from Homo sapiens (human). This epitope has been studied for immune reactivity in
9
publication(s), tested in
56
T cell assays,
20
B cell assays,
3
MHC ligand assays and has 3D structure(s)
7RE8
and
7RE7
.
CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s)
3
MHC moleculePositive / All
HLA-A*02:01
3
/
3
B Cell Assay(s)
20
Assay TypePositive / All
dissociation constant KD
5
/
5
off rate
5
/
5
on rate
5
/
5
secondary in vitro activity
2
/
2
antibody-dependent cellular cytotoxicity
1
/
1
qualitative binding
1
/
1
tumor burden after challenge after adoptive transfer
1
/
1
T Cell Assay(s)
56
Assay TypePositive / All
IFNg release
18
/
19
qualitative binding
8
/
12
cytotoxicity
7
/
8
IL-2 release
3
/
3
tumor burden after challenge after adoptive transfer
3
/
3
activation
2
/
2
degranulation
2
/
2
dissociation constant KD
2
/
2
granulysin release
1
/
1
granzyme A release
1
/
1
granzyme B release
1
/
1
proliferation
1
/
1
TNFa release
1
/
1
EXTERNAL RESOURCES
ResourceLink
IEDB-AR: MHC-I Processing
Predict MHC class I processing
IEDB-AR: MHC-I
Predict MHC class I binding affinity
IEDB-AR: B cell scales
Predict B cell epitopes