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| Article Authors: | Yoshihiko Murata; Paula M Lightfoote; Ann R Falsey; Edward E Walsh |
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| Article Title: | Identification of and human serum reactogenicity to neutralizing epitopes within the central unglycosylated region of the respiratory syncytial virus attachment protein. |
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| Reference ID: | 1019222 |
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| Abstract: | We identified two overlapping neutralizing epitopes within residues 151 to 172 of the central unglycosylated region of the respiratory syncytial virus (RSV) attachment protein. In approximately 40% of hospitalized and outpatient adults infected with RSV subtype A, these contiguous residues are the target of > or =4-fold increases in IgG response between acute- and convalescent-phase sera. |
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| Affiliations: | Division of Infectious Diseases, Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 689, Rochester, NY 14642, USA. Yoshihiko_Murata@urmc.rochester.edu |
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| Date: | 2010 |
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| Reference Type: | Literature |
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| PubMed ID: | 20164253 |
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| Journal: | Clin Vaccine Immunol |
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| Journal Volume: | 17 |
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| Article Pages: | 695-7 |
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| Journal ISSN: | 1556-6811 |
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| Article Chemical List: | Antibodies, Neutralizing;Antibodies, Viral;Epitopes;Immunoglobulin G;Viral Envelope Proteins;attachment protein G |
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| Article MeSH List: | Adult; Amino Acid Sequence; Antibodies, Neutralizing(blood); Antibodies, Viral(blood); Epitope Mapping; Epitopes(immunology); Humans; Immunoglobulin G(blood); Molecular Sequence Data; Respiratory Syncytial Virus, Human(immunology); Viral Envelope Proteins(immunology) |
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| Curation Last Updated: | 2013-05-28 22:07:52 |
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