Epitopes described in "Cross-recognition of N-formylmethionine peptides is a general characteristic of H2-M3-restricted CD8+ T cells."

Reference
Article Authors:Alexander Ploss; An Tran; Ewa Menet; Ingrid Leiner; Eric G Pamer
Article Title:Cross-recognition of N-formylmethionine peptides is a general characteristic of H2-M3-restricted CD8+ T cells.
Reference Detail
Reference ID:1118
Abstract:H2-M3-restricted CD8+ T cells can exhibit cross-reactivity to different bacterially derived N-formylmethionine peptides. The extent of this promiscuity is unclear. We deleted the nonredundant fMIVTLF epitope and found that Listeria monocytogenes still primed fMIVTLF-specific T cells. Thus, cross-reactivity appears to be a more general characteristic of H2-M3-restricted T cells.
Affiliations:Infectious Diseases Service, Department of Medicine and Laboratory of Antimicrobial Immunity, Immunology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.
Date:2005
Reference Type:Literature
PubMed ID:15972542
Journal:Infect Immun
Journal Volume:73
Article Pages:4423-6
Journal ISSN:1098-5522
Article Chemical List:Epitopes;H2-M3 antigen;Histocompatibility Antigens Class I;N-Formylmethionine
Article MeSH List:Animals; CD8-Positive T-Lymphocytes(immunology); Cross Reactions; Epitopes; Histocompatibility Antigens Class I(immunology); Listeria monocytogenes(immunology); Mice; Mice, Inbred C57BL; N-Formylmethionine(immunology)
Curation Last Updated:2011-08-23 20:21:17