EPITOPE SUMMARY
toluene 2,4-diisocyanate (epitope ID
115138
) has this structure:
CHEBI:53556
. The epitope has these synonyms: 2,4-diisocyanato-1-methylbenzene, 2,4-Diisocyanatotoluene, 2,4-TDI, 2,4-Toluene diisocyanate, 2,4-Tolylene diisocyanate, 4-Methyl-m-phenylene diisocyanate, Isocyanic acid, 4-methyl-m-phenylene ester, TDI, toluene-2,4-diyl diisocyanate, Toluylene-2,4-diisocyanate, Tolylene-2,4-diisocyanate. This epitope has been studied for immune reactivity in
20
publication(s), tested in
34
T cell assays and
48
B cell assays.
CURATED EXPERIMENTAL DATA
B Cell Assay(s)
48
Assay TypePositive / All
qualitative binding
35
/
41
hypersensitivity
4
/
5
association constant KA
1
/
1
disease exacerbation
1
/
1
T Cell Assay(s)
34
Assay TypePositive / All
type IV hypersensitivity (DTH)
4
/
4
IL-4 release
2
/
3
disease exacerbation
2
/
2
IFNg release
2
/
2
proliferation
1
/
2
CXCL10/IP-10 release
1
/
1
CXCL9/MIG release
1
/
1
IL-13 release
1
/
1
IL-17 release
1
/
1
IL-2 release
1
/
1
IL-5 release
1
/
1
IL-9 release
1
/
1
CCL17/TARC release
0
/
1
CCL19/MIP-3b release
0
/
1
CCL2/MCP-1 release
0
/
1
CCL21/SLC release
0
/
1
CCL22/MDC release
0
/
1
CCL4/MIP-1b release
0
/
1
CCL5/RANTES release
0
/
1
CCL9/MIP-1g release
0
/
1
CXCL12/SDF-1 release
0
/
1
CXCL13/BLC release
0
/
1
CXCL16 release
0
/
1
IL-1b release
0
/
1
IL-7 release
0
/
1
TNF release
0
/
1
EXTERNAL RESOURCES
ResourceLink
PubChem
11443